In humans, it is between 150 and 200 mg per kilogram (70-90 per pound.)Ĭaffeine is in many drinks and foods. The Lethal Dose 50 of caffeine is 192 mg per kilogram, in rats. More than 750–1000 mg a day is a significant amount, but is very unlikely to kill someone. That is as much caffeine that is in three cups of coffee (8oz each cup). How much caffeine is safe Ģ50–300 mg of caffeine a day is a moderate amount.
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